This study investigates the manufacture of mPEG-PLA diblock copolymers through a controlled polymerization technique. Various reaction conditions, including monomer concentration, were varied to achieve desired molecular weights and polydispersity indices. The resulting copolymers were analyzed using techniques such as gel permeation chromatography

mPEG-PLA diblock polymer nanocarriers present a effective platform for enhancing controlled drug release. These nanocarriers consist a hydrophilic methylene PEGmPEG block and a lipophilic poly(lactic acid) PLA block, enabling them to self-assemble into homogeneous nanoparticles. The PEGylated exterior imparts water dispersibility, while the PLA cor